ZIKA virus infection causes persistent chorioretinal lesions

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منابع مشابه

Zika Virus Causes Persistent Infection in Porcine Conceptuses and may Impair Health in Offspring

Outcomes of Zika virus (ZIKV) infection in pregnant women vary from the birth of asymptomatic offspring to abnormal development and severe brain lesions in fetuses and infants. There are concerns that offspring affected in utero and born without apparent symptoms may develop mental illnesses. Therefore, animal models are important to test interventions against in utero infection and health sequ...

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Corrigendum to “Zika Virus Causes Persistent Infection in Porcine Conceptuses and May Impair Health in Offspring”

a Vaccine and Infectious Disease Organization-International Vaccine Centre (VIDO-InterVac), University of Saskatchewan, Saskatoon, SK S7N 5E3, Canada b Department of Physiology, Department of Obstetrics and Gynaecology, University of Toronto, Toronto, ON M5S 1A8, Canada c Department of Small Animal Clinical Sciences, Western College of Veterinary Medicine, University of Saskatchewan, Saskatoon,...

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Zika virus infects cells lining the blood-retinal barrier and causes chorioretinal atrophy in mouse eyes.

Zika virus (ZIKV) is an important pathogen that causes not only neurologic, but also ocular, abnormalities. Thus, it is imperative that models to study ZIKV pathogenesis in the eye are developed to identify potential targets for interventions. Here, we studied ZIKV interactions with human retinal cells and evaluated ZIKV's pathobiology in mouse eyes. We showed that cells lining the blood-retina...

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ژورنال

عنوان ژورنال: Emerging Microbes & Infections

سال: 2018

ISSN: 2222-1751

DOI: 10.1038/s41426-018-0096-z